This is the #1 cause. Modern antivirus tools (including Microsoft Defender) are hyper-sensitive to any process that modifies boot sectors or system files—exactly what Rufus does.

If you see “Unable to patch/setup files for boot,” follow this rescue sequence:

: Windows Defender’s "Controlled Folder Access" can prevent Rufus from partitioning or writing to the drive. You must either disable this feature temporarily or add Rufus to the whitelist.

Rufus Unable To Patch/setup Files For Boot Page

This is the #1 cause. Modern antivirus tools (including Microsoft Defender) are hyper-sensitive to any process that modifies boot sectors or system files—exactly what Rufus does.

If you see “Unable to patch/setup files for boot,” follow this rescue sequence: rufus unable to patch/setup files for boot

: Windows Defender’s "Controlled Folder Access" can prevent Rufus from partitioning or writing to the drive. You must either disable this feature temporarily or add Rufus to the whitelist. This is the #1 cause