: Known for the Maestro Pro and Edge platforms.
The system captures high-dimensional data that reflects both individual cell health and network-wide communication: : The frequency of individual action potentials.
: Unlike single-well systems, multiwell plates (typically in 24, 48, or 96-well formats ) contain an array of microelectrodes at the bottom of every well. This allows for high-throughput screening where dozens of independent experiments run at once.
The utility of multiwell MEA spans nearly every domain of electrogenic cell research.
A is a sophisticated electrophysiology platform designed for high-throughput, non-invasive recording of extracellular electrical activity from networks of excitable cells, such as neurons and cardiomyocytes. By integrating multiple independent culture wells into a single plate—often following standard 12, 24, 48, or 96-well formats—this technology allows researchers to conduct dozens of experiments simultaneously. The Core Technology: How it Works
At its core, a multiwell MEA is a marriage of two established tools: the standard 24-, 48-, or 96-well microplate and the planar microelectrode array. Each well contains a grid of tiny, corrosion-resistant electrodes (typically made of gold, platinum, or indium tin oxide) embedded in its glass or polymer base. When cells—such as neurons, cardiac myocytes, or pancreatic beta cells—are cultured directly atop these electrodes, they form intimate electrical junctions. As the cells fire action potentials, the resulting local field potentials are detected in real-time by the electrodes beneath them.