The 4.5.2 release introduced significant reliability, performance, and security enhancements over versions 4.5 and 4.5.1. Enhanced High-DPI Support Rescales Windows Forms controls reliably. Fixes blurry text in high-resolution displays. Stabilizes layouts in enterprise desktop applications. Advanced ASP.NET Capabilities
If you are starting a new software project, bypass this legacy version. Move toward modern frameworks to secure long-term support, cross-platform deployments, and cloud optimization: .net framework 4.5.2 developer pack