For $2 \times 2$ tables, some statisticians prefer Yates' continuity correction. Prism offers this as an option in the parameters window (" Yates' correction (recommended)"). In modern statistics, Fisher’s Exact Test is generally preferred over Yates' correction for small samples, so sticking with the default or Fisher's is usually best.
Unlike spreadsheets where you enter raw data row by row, Prism expects . chi square graphpad
You do not have to calculate the counts yourself before entering Prism. For $2 \times 2$ tables, some statisticians prefer
| | Placebo | Vaccine | | :--- | :--- | :--- | | | 45 | 15 | | Not Infected | 55 | 85 | For $2 \times 2$ tables